Khurana RK, Gaspar BL, Welsby G, Katare OP, Singh KK, Singh B (2018) Improving the

biopharmaceutical attributes of mangiferin using vitamin E-TPGS co-loaded self-assembled

phosholipidic nanomixed micellar systems. Drug Deliv Transl Res 8(3):617–632

Korting S, Monika (2010) Drug delivery. Springer-Verlag, Berlin Heidelberg, New York

Kumar S, Xu X, Gokhale R, Burgess DJ (2014) Formulation parameters of crystalline

nanosuspensions on spray drying processing: a DoE approach. Int J Pharm 464(1–2):34–45

Lena Leopold L, Zhao CC, McConnachie LL, Khurana RK, Sharma T, Singh B et al (2018) Surface

engineered nanomaterial: environmental and safety considerations in pharmaceutical and

medicinal products. In: Singh B, Kanwar JR, Garg S (eds) NanoBioEngineering. CRC Press,

USA, pp 297–310

Lewis GA (2002) Optimization methods. In: Swarbrick J, Boylan JC (eds) Encyclopedia of

pharmaceutical technology, 2nd edn. Marcel Dekker, New York

Lewis GA, Mathieu D, Phan-Tan-Luu R (1998) Pharmaceutical Experimental Design. CRC

Press, USA

Li J, Qiao Y, Wu Z (2017) Nanosystem trends in drug delivery using quality-by-design concept. J

Control Release 256:9–18

Lohan S, Raza K, Mehta SK, Bhatti GK, Saini S, Singh B (2017) Anti-Alzheimer's potential of

berberine using surface decorated multi-walled carbon nanotubes: a preclinical evidence. Int J

Pharm 530(1):263–278

Martins GA, Murakami FS, Oliveira MS, Furian AF, Treichel H, Mainardes RM et al (2020)

Development of polymeric nanocarriers for brain targeted delivery of atorvastatin: a quality-by-

design approach. Drug Deliv Lett 10(2):149–158

Ministry of Health Labour and Welfare Japan (2016) Guideline for the development of liposome

drug products. http://www.nihs.go.jp/drug/section4/160328_MHLW_liposome_guideline.pdf.

Accessed 13 Apr 2019

Mody VV, Siwale R, Singh A, Mody HR (2010) Introduction to metallic nanoparticles. J Pharm

Bioallied Sci 2(4):282–289

Momin M, Disouza J, Patravale V (2016) Advances in technology and business potential of new

drug delivery systems. Drug Deliv Transl Res 6(4):341

Montgomery DC (2001) Design and analysis of experiments. Wiley, New York

Moolakkadath T, Aqil M, Ahad A, Imam SS, Iqbal B, Sultana Y et al (2018) Development of

transethosomes formulation for dermal fisetin delivery: Box–Behnken design, optimization,

in vitro skin penetration, vesicles–skin interaction and dermatokinetic studies. Artif Cells

Nanomed Biotechnol 46:1–11

Nadaf SJ, Killedar SG (2018) Curcumin nanocochleates: use of design of experiments, solid state

characterization, in vitro apoptosis and cytotoxicity against breast cancer MCF-7 cells. J Drug

Deliv Sci Tec 47:337–350

Nadia AA, Leila R, Mohammad I, Ismaeil H (2015) Fabrication of PLA/PEG/MWCNT electrospun

nanofibrous scaffolds for anticancer drug delivery. J Appl Polym Sci 132(3):1–9

Nagpal K, Kumar P, Mohan A, Thakur S (2019) Dendrimers for therapeutic delivery: compositions,

characterizations, and current status. Crit Rev Ther Drug Carrier Syst 36:277–304

Nanda S, Nanda A, Singh B (2015) Federal perspectives of nanostructured systems: an update. In:

Singh B, Vyas SP, Kaur IP (eds) Nanostructured drug delivery, vol 4. Studium Press, LLC,

New York, pp 491–525

Nemati F, Zare-Dorabei R, Hosseini M, Ganjali MR (2018) Fluorescence turn-on sensing of

thiamine based on arginine-functionalized graphene quantum dots (Arg-GQDs): central com-

posite design for process optimization. Sens Actuators B Chem 255:2078–2085

Niu L, Panyam J (2017) Freeze concentration-induced PLGA and polystyrene nanoparticle aggre-

gation: imaging and rational design of lyoprotection. J Control Release 248:125–132

Pallagi E, Ambrus R, Szabó-Révész P, Csóka I (2015) Adaptation of the quality by design concept

in early pharmaceutical development of an intranasal nanosized formulation. Int J Pharm

491(1–2):384–392

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